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Spyre Therapeutics, Inc. (SYRE) Market Cap & Valuation Ratios

Spyre Therapeutics, Inc. (SYRE) has a market cap of $8.0B, with earnings according to EquiReason's reading of its SEC filings.

Source: SEC EDGAR filings · figures as of 2026-06-30 · read by EquiReason

SYRESpyre Therapeutics, Inc.Follow SYRE — free
Biotechnology · Healthcare
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Price chart with a free account
Market cap
8.0B
P/E TTM
—
Dividend yield
—
52-week
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Next earnings
5 Nov, in 12 days

Peers

biotechnology · nearest by market cap · trailing 12 months
CompanyMkt cap, $BP/EEV/SalesEV/EBITDAFCF yieldRev. growthOp. marginROIC
SYRE8.0———-2.6%——-31%
CAI9.085.68.749.71.4%+85%15%61%
PCVX9.0———-10.2%——-44%
PTGX9.0135.729.0136.51.5%+35%21%12%
IBRX8.7—57.6—-3.3%+193%-152%-319%
CYTK8.5—125.5—-6.8%-21%—-99%
TGTX8.319.710.662.20.2%+76%17%17%
ARWR8.2—11.1—-0.9%+17%-34%-24%
AXSM7.6—9.6—-0.9%+57%-24%—
IONS7.1—7.3—-7.9%-7%-68%-42%
PRAX7.1———-4.3%——-68%
Median of these 1085.610.962.2-2.1%+46%-24%-42%

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Growth vs. price

each dot a company · hover or tap for values
20501000%+25%+50%+75%revenue growth, TTM →P/E (log)CAIPTGXTGTX

SYRE and PCVX and IBRX and CYTK and ARWR and AXSM and IONS and PRAX have no P/E (earnings not positive) and are left out · hover or tap a dot for values.

Spyre Therapeutics, Inc. — questions

What is Spyre Therapeutics, Inc.'s market cap?
$8.0B.

Every figure on this page comes from Spyre Therapeutics, Inc.'s own SEC filings — see them on SEC EDGAR. Price data is licensed and shown only inside the product.

How these figures are read: methodology · EquiReason.