Ionis Pharmaceuticals, Inc. (IONS) Profit Margins
Over the twelve months to 2026-06-30, Ionis Pharmaceuticals, Inc. (IONS) had operating margin -68.0%, net margin -64.7%, free cash flow margin -64.2%, according to EquiReason's reading of its SEC filings.
Source: SEC EDGAR filings · figures as of 2026-06-30 · read by EquiReason
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| Line | FY2010 Dec 10 | FY2011 Dec 11 | FY2012 Dec 12 | FY2013 Dec 13 | FY2014 Dec 14 | FY2015 Dec 15 | FY2016 Dec 16 | FY2017 Dec 17 | FY2018 Dec 18 | FY2019 Dec 19 | FY2020 Dec 20 | FY2021 Dec 21 | FY2022 Dec 22 | FY2023 Dec 23 | FY2024 Dec 24 | FY2025 Dec 25 | TTM Jun 26 | Trend |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross margin | — | — | — | — | — | — | — | — | 99.7% | 99.6% | 98.4% | 98.7% | 97.6% | 98.8% | 98.4% | 98.3% | — | |
| Operating margin | -44.6% | -71.8% | -67.5% | -35.1% | -22.3% | -26.7% | -5.8% | 6.1% | -10.2% | 32.6% | -23.6% | -3.7% | -69.8% | -44.9% | -67.4% | -40.4% | -68.0% | |
| Net margin | -56.5% | -85.6% | -64.2% | -41.2% | -18.2% | -31.1% | -17.4% | 0.1% | 45.6% | 24.8% | -60.9% | -3.5% | -45.9% | -46.5% | -64.4% | -40.4% | -64.7% | |
| FCF margin | -70.8% | -126.2% | 0.4% | 42.1% | -0.6% | 4.7% | -34.4% | 27.5% | 98.3% | 28.0% | 0.1% | 2.3% | -49.4% | -42.1% | -77.5% | -33.9% | -64.2% |
USD billions · SEC XBRL
Ionis Pharmaceuticals, Inc. — questions
- What is Ionis Pharmaceuticals, Inc.'s operating margin?
- -68.0% over the twelve months to 2026-06-30.
- What is Ionis Pharmaceuticals, Inc.'s net profit margin?
- -64.7% over the twelve months to 2026-06-30.
Every figure on this page comes from Ionis Pharmaceuticals, Inc.'s own SEC filings — see them on SEC EDGAR. Price data is licensed and shown only inside the product.
How these figures are read: methodology · EquiReason.