Charles River Laboratories International, Inc. (CRL) SEC Filings & Earnings Calls
EquiReason read 17 Charles River Laboratories International, Inc. SEC filings in the last 12 months. Latest: 8-K on 2026-09-24 — Charles River Laboratories reaffirms FY2026 guidance, expects revenue and non-GAAP EPS at upper ends of prior ranges; introduces 2030 targets: 5-7% organic revenue CAGR, ~24% non-G.
Source: SEC EDGAR filings · figures as of 2026-06-30 · read by EquiReason
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last 12 months · SECWhat happened, the numbers inside, guidance and risks. The original is one click away.
24 Sep 20268-K · 7.01Charles River Laboratories reaffirms FY2026 guidance, expects revenue and non-GAAP EPS at upper ends of prior ranges; introduces 2030 targets: 5-7% organic revenue CAGR, ~24% non-GAAP operating margin.open
Figures in the filing · each found in the filing text
| Revenue growth, organic · FY2026 | 1.0% | |
| Non-GAAP operating margin · FY2026 | 21.3% | |
| Non-GAAP EPS · FY2026 | $11.45 | |
| Bioanalysis revenue · Bioanalysis · 2030 | $450M |
Guidance
FY2026 revenue growth organic upper end of 0-1%; Non-GAAP operating margin 21.0-21.3%; Non-GAAP EPS upper end of $11.15-$11.45; 2030 targets: organic revenue CAGR 5-7%, non-GAAP operating margin ~24%, non-GAAP EPS low-double-digit CAGR
Reaffirmed FY2026 guidance with expectation of upper end; introduced long-term targets through 2030 indicating confidence in growth and margin expansion.
Risks flagged
Long-term targets are aspirational and subject to significant uncertainties; not projections or guidance.
“The financial targets are not projections and do not constitute financial guidance; they are subject to significant uncertainties and contingencies and are based upon management's current assumptions, which are subject to change.” · word for word
5 Aug 202610-QCharles River divested CDMO, Cell Solutions, and European Discovery Services businesses, incurring significant losses and restructuring its portfolio.open
Figures in the filing · each found in the filing text
| Total revenue · Q2-2026 | $1.00B | -3% y/y |
| Net income (loss) attributable to common shareholders · Q2-2026 | $-1M | |
| Operating cash flow · H1-2026 | $221M | -41% y/y |
| DSA revenue · Discovery and Safety Assessment · Q2-2026 | $607M | -2% y/y |
| Manufacturing revenue · Manufacturing Solutions · Q2-2026 | $188M | -6% y/y |
| RMS revenue · Research Models and Services · Q2-2026 | $209M | -2% y/y |
| Operating income · Q2-2026 | $120M | +20% y/y |
| Capital expenditures · Q2-2026 | $31M | -12% y/y |
Risks flagged
Divestiture execution risk
“Pre-tax loss on CDMO and Cell Solutions Divestiture $181.7 million; net cash paid to buyer $12.4 million.”
NHP supply chain risk
“Acquisition of Cambodian NHP supplier for $507.3 million with $172.3 million deferred consideration.”
Revenue decline risk
“Total revenue declined 2.7% YoY in Q2; all three segments reported lower revenue.”
5 Aug 20268-K · 2.02Revenue $1.00B (-3% y/y); GAAP loss per share $-0.03; Non-GAAP earnings per share $3.02 (-3% y/y); Guidance: Organic revenue guidance up 150bps; non-GAAP EPS guidance up $0.25 at midpointearningsopen
Figures in the filing · each found in the filing text
| Revenue · Q2-2026 | $1.00B | -3% y/y |
| GAAP loss per share · Q2-2026 | $-0.03 | |
| Non-GAAP earnings per share · Q2-2026 | $3.02 | -3% y/y |
| Non-GAAP operating margin · Q2-2026 | 20.5% | |
| Organic revenue growth · Q2-2026 | 0.1% | |
| RMS segment revenue · RMS · Q2-2026 | $210M | -2% y/y |
| DSA segment revenue · DSA · Q2-2026 | $607M | -2% y/y |
Guidance
Organic revenue guidance up 150bps; non-GAAP EPS guidance up $0.25 at midpoint
Company raises 2026 revenue and non-GAAP EPS guidance, citing improving demand in DSA and better-than-expected Manufacturing performance.
Risks flagged
Revenue still declining YoY despite sequential improvement; RMS segment continues to shrink.
“Revenue decreased 2.7% YoY; RMS organic revenue -1.4%”
Divestitures may reduce future revenue base and create execution risk.
“Completed divestitures of certain European Discovery Services sites as well as the CDMO and Cell Solutions businesses in May 2026.”
7 May 20268-K · 2.02Revenue $996M (+1% y/y); Non-GAAP earnings per share $2.06 (-12% y/y); GAAP net loss available to common shareholders $-15M; Guidance: Organic revenue and non-GAAP EPS guidance reaffirmedearningsopen
Figures in the filing · each found in the filing text
| Revenue · Q1-2026 | $996M | +1% y/y |
| Non-GAAP earnings per share · Q1-2026 | $2.06 | -12% y/y |
| GAAP net loss available to common shareholders · Q1-2026 | $-15M |
Guidance
Organic revenue and non-GAAP EPS guidance reaffirmed
Guidance reaffirmed; management expects improving results over the year.
Risks flagged
Organic revenue decline and margin pressure from higher costs.
“Organic revenue declined 1.5%, non-GAAP operating margin decreased 280 bps.”
Divestiture of CDMO and Cell Solutions businesses completed; loss on assets held for sale $118M.
“Loss on assets held for sale related to the CDMO and Cell Solutions divestiture totaling $118.0 million.” · word for word
7 May 202610-QRevenue $996M (+1% y/y); Net income (loss) attributable to common shareholders $-15M; Operating cash flow $41M (-76% y/y)open
Figures in the filing · each found in the filing text
| Revenue · Q1-2026 | $996M | +1% y/y |
| Net income (loss) attributable to common shareholders · Q1-2026 | $-15M | |
| Operating cash flow · Q1-2026 | $41M | -76% y/y |
| DSA backlog · DSA · Q1-2026 | $1.90B |
Risks flagged
Persistent demand weakness in DSA
“We are continuing to see a cautious spending environment from our client base, principally within our DSA segment as the challenging demand environment experienced in the recent prior quarters has persisted.” · word for word
Large impairment from divestiture
“Net loss attributable to Charles River Laboratories International, Inc., common shareholders was $14.8 million ... due principally to the loss on assets held for sale related to the CDMO and Cell Solutions Divestiture of $118.0 million.” · word for word
Declining operating cash flow
“During the three months ended March 28, 2026, our cash flows from operations were $41.1 million compared with $171.7 million for the same period in 2025.” · word for word
31 Mar 2026DEF 14AProxy statement filed for 2026 annual meeting, detailing executive compensation, pay-for-performance alignment, CEO succession, strategic review including divestitures, and a $1.0B buyback authorization.open
Figures in the filing · each found in the filing text
| Operating Cash Flow · FY2025 | $738M | +0% y/y |
| GAAP Diluted EPS · FY2025 | $-2.91 | |
| Non-GAAP Net Income · FY2025 | $512M | |
| Shares Repurchased · FY2025 | 2,100,000 | |
| Stock Repurchase Authorization · 2025-10-29 | $1.00B | |
| Goodwill Impairment · Biologics Solutions · FY2025 | $165M | |
| 2025 EICP Bonus Payout · FY2025 | 139.0% | |
| 2023 PSU Payout · FY2025 | 87.3% | |
| Non-GAAP Operating Income (EICP Target) · FY2025 | $794M |
Risks flagged
Goodwill and Intangible Asset Impairment Risk
“The primary driver of the GAAP decrease were non-cash intangible asset and goodwill impairments of $211.0 million and $165.0 million, respectively, in the fourth quarter of 2025.” · word for word
NHP Supply Chain Risk
“Third-party legal costs incurred are associated with investigations by the U.S. government into the NHP supply chain.” · word for word
Restructuring and Divestiture Execution Risk
“Most recently, we announced the planned divestitures of the contract development and manufacturing products and services (CDMO) and Cell Solutions businesses and certain European sites within the Discovery Services business.” · word for word
CEO Succession Risk
“In connection with the announcement of Ms. Girshick’s appointment as our Chief Executive Officer, effective May 5, 2026, the Company entered into a letter agreement with Ms. Girshick.” · word for word
25 Feb 20268-K · 7.01CDMO and Cell Solutions Revenue $143M; European Discovery Services Revenue $144M; 2026 Reported Revenue Growth Guidance (including divestitures) -3.5; Guidance: Reported revenue guidance cut to (5.0)% to (3.5)% from at least flat to +1.5%;open
Figures in the filing · each found in the filing text
| CDMO and Cell Solutions Revenue · Manufacturing Solutions; RMS · FY2025 | $143M | |
| European Discovery Services Revenue · DSA · FY2025 | $144M | |
| 2026 Reported Revenue Growth Guidance (including divestitures) · FY2026 | -3.5% | |
| 2026 Organic Revenue Growth Guidance (including divestitures) · FY2026 | -0.5% | |
| 2026 Non-GAAP EPS Guidance (including divestitures) · FY2026 | $11.30 | |
| European Discovery Cash Proceeds · Q2-2026 | $145M |
Guidance
Reported revenue guidance cut to (5.0)% to (3.5)% from at least flat to +1.5%; organic cut to (1.5)% to (0.5)% from (1.0)% to at least flat.
Guidance cut due to planned divestitures; revenue down but margins and EPS improve.
Risks flagged
Divestiture execution risk; potential disruption to ongoing operations.
“subject to customary closing conditions” · word for word
Revenue decline from divestitures may pressure near-term top-line growth.
“reduce reported revenue by slightly more than $200 million in 2026” · word for word
18 Feb 202610-KTotal Revenue $4.00B; RMS Segment Revenue % 21.1; DSA Segment Revenue % 59.8open
Figures in the filing · each found in the filing text
| Total Revenue · FY2025 | $4.00B | |
| RMS Segment Revenue % · RMS · FY2025 | 21.1% | |
| DSA Segment Revenue % · DSA · FY2025 | 59.8% | |
| Manufacturing Segment Revenue % · Manufacturing · FY2025 | 19.1% |
Risks flagged
Non-Human Primate Supply Chain Disruption
“We may use forward-looking statements when addressing topics such as: our expectations regarding the availability of non-human primates and our ability to diversify our non-human primate (NHP) supply chain.” · word for word
Demand Slowdown in Biopharma
“While the biopharmaceutical demand environment has been less robust in recent years” · word for word
18 Feb 20268-K · 2.02Revenue $994M (-1% y/y); GAAP Loss per Share $-5.62; Non-GAAP Earnings per Share $2.39 (-10% y/y)earningsopen
Figures in the filing · each found in the filing text
| Revenue · Q4-2025 | $994M | -1% y/y |
| GAAP Loss per Share · Q4-2025 | $-5.62 | |
| Non-GAAP Earnings per Share · Q4-2025 | $2.39 | -10% y/y |
| GAAP Net Loss · Q4-2025 | $-277M | |
| Non-GAAP Net Income · Q4-2025 | $119M | -13% y/y |
| GAAP Operating Margin · Q4-2025 | -28.5% | |
| Non-GAAP Operating Margin · Q4-2025 | 18.1% | |
| RMS Revenue · RMS · Q4-2025 | $206M | +1% y/y |
| DSA Revenue · DSA · Q4-2025 | $592M | -2% y/y |
| Manufacturing Revenue · Manufacturing · Q4-2025 | $196M | +1% y/y |
Risks flagged
Significant impairment charges indicate potential overvaluation of acquired assets and ongoing restructuring.
“$376M in impairment charges ($211M intangible, $165M goodwill) in Biologics Solutions and Cell Solutions.”
Margin pressure from higher direct costs and unfavorable mix may persist.
“Non-GAAP operating margin decreased to 18.1% from 19.9% due to lower revenue and higher costs.”
18 Feb 20268-K · 5.02Reported the departure of a director or principal officer (CEO/CFO change); filed financial statements and exhibits with this reportopen
Risks flagged
Leadership transition may introduce execution risk, but appointment of an internal candidate (likely) mitigates this.
“Departure of a director or principal officer (CEO/CFO change) with a new CFO appointment.”
13 Jan 20268-K · 2.02, 7.01DSA net book-to-bill ~1.1x in Q4 2025; 2026 revenue guidance top end at least flat; >$100M cost savings; two acquisitions totaling ~$570M; NHP supply vertical integration and NGS quality-control expansion.open
Figures in the filing · each found in the filing text
| DSA net book-to-bill · DSA · Q4-2025 | $1.10 |
Guidance
FY2026 organic revenue growth at least flat; non-GAAP operating margin improvement from >$100M cost savings; FX benefit 100-150 bps; DSA revenue growth expected in H2 2026.
Demand improving in DSA; cost savings support margin; revenue growth expected in H2 2026; acquisitions add strategic value but near-term revenue impact modest.
Risks flagged
RMS headwinds from NHP shipment timing and CRADL occupancy may offset Manufacturing growth.
“Expected improvement in Manufacturing organic revenue growth will be offset by anticipated RMS headwinds from timing of NHP shipments and CRADL occupancy” · word for word
Integration risk from two acquisitions; PathoQuest revenue modest ($15-20M) and not material near-term.
“PathoQuest SAS is expected to generate annual revenue of approximately $15 to $20 million in 2026. The transaction is not expected to have a material impact on Charles River’s 2026 or 2027 GAAP or non-GAAP financial results.” · word for word
9 Jan 20268-K · 5.02Reported a director or officer change (departure, election, appointment or pay arrangement)open
Risks flagged
Leadership transition risk; activist involvement may signal strategic changes.
“Elliott Investment Management L.P provided limited consent under Cooperation Agreement”
3 Dec 20258-K · 7.01Charles River Laboratories provided an update on DSA segment demand trends: net book-to-bill has improved each month since Q3 2025, with positive momentum continuing into Q4 despite seasonal effects.open
Risks flagged
Seasonality in Q4 and early January may impact near-term proposal and booking activity.
“While seasonality during holiday periods in the fourth quarter and in early January may impact near-term proposal and booking activity” · word for word
17 Nov 20258-K · 8.01Disclosed a material event under other events (litigation, recall, contract loss, or major announcement)open
Risks flagged
Regulatory risk from SEC investigation now resolved; no material findings.
“the SEC’s Division of Enforcement...does not intend to recommend an enforcement action”
5 Nov 202510-QCharles River reported Q3 2025 revenue of $1.005B (-0.5% YoY), with DSA and Manufacturing segments declining due to cautious client spending; net income fell 21% YoY; company announced strategic review and new $1B buyback authorization.earningsopen
Figures in the filing · each found in the filing text
| Revenue · Q3-2025 | $1.00B | -1% y/y |
| Net income available to common shareholders · Q3-2025 | $54M | -21% y/y |
| Operating cash flow · 9M-2025 | $590M | +3% y/y |
| DSA backlog · DSA · Q3-2025 | $1.80B | |
| RMS operating margin · RMS · Q3-2025 | 16.2% | |
| DSA operating margin · DSA · Q3-2025 | 20.5% | |
| Manufacturing operating margin · Manufacturing · Q3-2025 | 20.9% | |
| Share repurchases · 9M-2025 | $350M | +194% y/y |
Risks flagged
SEC investigation into NHP supply chain
“On May 16, 2023, we received an inquiry from the Enforcement Division of the U.S. Securities and Exchange Commission (SEC) requesting us to voluntarily provide information, subsequently augmented with a document subpoena and additional inquiries, primarily related to the sourcing of non-human primates and related disclosures, and we are cooperating with the ” · word for word
Loss of key CDMO customers
“The decreases in operating income and operating income as a percentage of revenue for the nine months ended September 27, 2025 were primarily driven by the acceleration of amortization expense recognized as a result of a decrease in the remaining useful life of certain CDMO client relationships due to a loss of key customers.” · word for word
Tariff uncertainty
“The extent and duration of these tariffs and the resulting impact on macroeconomic conditions and our business are uncertain and may depend on various factors including, but not limited to, negotiations between the U.S. and affected countries, reciprocal or retaliatory actions imposed by other countries, tariff exemptions, negative sentiment toward U.S. comp” · word for word
Government contract awards
federal awards · contract value, often multi-year| Date | Agency | Value | What for |
|---|---|---|---|
| 2026-09-17 | National Institutes of Health | $8M | TASK ORDER 5 FOR THE DEVELOPMENT AND MAINTENANCE OF A MULTIGENOTYPIC AGED MOUSE COLONY. |
| 2026-03-13 | National Institutes of Health | $33M | THE PURPOSE OF THIS MODIFICATION IS TO EXERCISE TERM OPTION 2. |
| 2026-02-28 | National Institutes of Health | $6M | NATIONAL INSTITUTES OF HEALTH (NIH), NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE (NINDS), ANIMAL CARE AND RESEARCH SUPPORT SERVICES LARC-2025-NINDS-0010 |
Charles River Laboratories International, Inc. — questions
- What did Charles River Laboratories International, Inc. file recently?
- 17 SEC filings in the last 12 months. Latest: 8-K on 2026-09-24 — Charles River Laboratories reaffirms FY2026 guidance, expects revenue and non-GAAP EPS at upper ends of prior ranges; introduces 2030 targets: 5-7% organic revenue CAGR, ~24% non-GAAP operating margin.
Every figure on this page comes from Charles River Laboratories International, Inc.'s own SEC filings — see them on SEC EDGAR. Price data is licensed and shown only inside the product.
How these figures are read: methodology · EquiReason.